Squip's Nasaline Salt - 12oz/340g Pouch is saline used for large volume/low pressure saline nasal irrigation, moisturization, daily nasal hygiene. Each 12 ounce pouch contains 99.99% highly purified, pharmaceutical grade sodium chloride, free of additives, preservatives, and anti-caking agents. The pouch makes 135+ cups of an isotonic saline mixture, when mixed with 8 ounces of warm distilled, sterilized, or filtered tap water (use a filter with an absolute pore size of 1 micron or smaller). Once mixed, use the saline mixture within 24 hours or discard.