Fully Active Folate supplies the B vitamin folate as [6S]-5-methyltetrahydrofolic acid (MTHF). This is the body’s most fully active folate nutrient, its most important folate reservoir, and the only folate form biochemically identical to the MTHF present in the body. This supplement features Quatrefolic**, human-identical MTHF, as a glucosamine salt. This next-generation supplement guarantees the intricate MTHF structure with improved stability over the earlier-generation calcium salt of MTHF.
Named after the Latin word for leaf ('folium'), folate is the collective term for a family of pteroylglutamate nutrients that are most concentrated in leafy vegetables. The body cannot make folate on its own and must obtain it from foods or dietary supplements, with possible small contributions from intestinal bacteria. Foods supply only limited amounts of folates and these are generally not well absorbed. Of the folates that are absorbed, almost all are converted to MTHF. The Quatrefolic** brand of MTHF in this supplement is the most stable and best-absorbed form available anywhere.
Some enzymes use methyl available from MTHF to produce certain purines and pyrimidines, which are building blocks for the bio-synthesis of DNA and RNA. DNA is the genetic 'blueprint' for making functional proteins, while RNA helps translate the blueprint into the final protein structure. MTHF is the body’s ultimate methyl reservoir, its most dependable source for obtaining methyl groups to build DNA and RNA, and from them proteins and phospholipids as needed.
