Carnitine has many important metabolic functions.It plays a very important role infat metabolism. It is essential for transporting long-chain fatty acid molecules (acylCoA) from the cytosol into the mitochondria of cells in the form of acylcarnitine. The aylcarnitine is then shuttled across the inner mitochondrlal membrane where it is reconjugated to form acylCoA. The free carnitine molecule is then shuttled back to pick up another acyl moiety. This specialized transport mechanism which is tightly regulated is known as the
"carnitine shuttle". Thuscarnitine supplies the necessary fuel for oxidation in the electron transport chain to produce vital biological energyCarnitine has also been shown to augment the aerobic metabolism of carbohydrates and enhance oxidative phosphorylationRecent research indicates thatcarnitine also functions as a metabolic antioxidant. There is evidence to show that carnitine can counter the adverse effects of increased free radical production observed in a number of pathologic conditions. In addition to scavenging free radicals, carnitine can also chelate iron.Each serving size of1 capsule provides 450 mg of L-Carnitine Fumaratewhich delivers 250 mg of elemental Carnitine.
It is the most stable Carnitine available and readily, the most bioavailable. It has been developed and patented by Sigma Tau, the largest pharmaceutical supplier of Carnitine, with 70% of the world's research directed to Carnitine.